Antidepressants in the management of bipolar depression - An appraisal

Abstract

The issue about whether and when to use antidepressants in bipolar depression is a clinical question that has generated a lot of passionate debate. There seems to be a discrepancy in the opinions of experts across the Atlantic Ocean about the pros and cons of using antidepressants for management of bipolar depression. This is amply reflected by the greater volume of discussion and opinion related scientific literature, rather than hardcore clinical data in the form of randomized controlled trials. The debate as of present exists with no final winner still as the use of antidepressants in bipolar depression has both pros and cons. This essay attempts to offer evidence to either of the viewpoints and offer some suggestions based on literature.