Anti-dandruff shampoo formulation with active substances Ethanol extract of Brassica oleracea var capitata L. and its verifying activity against fungus Malassezia furfur

Abstract

Traditionally cabbage (Brassica oleracea var. capitate L.) is often used by Indonesian society to deal with itching on the scalp due to the fungus Malassezia furfur which causes dandruff. Based on the results of previous studies, the antifungal activity test of cabbage leaf ethanol extract shows that ethanol extract has antifungal activity against Malassezia furfur. fungus. This research, an anti-dandruff shampoo formulation was carried out with the active ingredient of cabbage ethanol extract and verifying its activity test on M. furfur by diffusion method for the perforation method. The results showed that the preparation of anti-dandruff shampoo with active ingredients of cabbage ethanol extract had antifungal activity against M. furfur. The greater the concentration of cabbage ethanol extract in the shampoo, the greater the inhibitory power produced against M. furfur. Shampoo preparations made with cabbage ethanol extract concentrations of 15% and 30% had color, odor, shape, viscosity, surface tension, pH, high foam, and potential for anti-dandruff to be sufficient, safe to use, and stable for 8 weeks of storage. The anti-dandruff shampoo with 45% cabbage ethanol extract experienced changes in color, odor, and decreased viscosity during storage. It concluded that formulation shampoo with 15% but not higher than 45% cabbage ethanol extract suitable for an anti-dandruff shampoo.