Abstract
Catheter ablation (CA) of atrial fibrillation and flutter is associated with a high risk of both perioperative thromboembolic events and bleeding. Adequate anticoagulation is imperative to reduce the risk of complications. The aim of this review was to analyze modern approaches to anticoagulant therapy for CA of atrial fibrillation and flutter, as well as provide practical information based on a comparison of current guidelines and evidence base. The search for literature sources on anticoagulant therapy in CA was carried out in the PubMed, Scopus, Web of Science databases. The results of key randomized trials and meta-analyzes are presented, and a comparison of current Russian and international guidelines is given. Unresolved issues requiring further research are discussed.
Highlights
Catheter ablation (CA) of atrial fibrillation and flutter is associated with a high risk of both perioperative thromboembolic events and bleeding
The aim of this review was to analyze modern approaches to anticoagulant therapy for CA of atrial fibrillation and flutter, as well as provide practical information based on a comparison of current guidelines and evidence base
VENTURE-AF (ActiVe-controlled multi-cENTer stUdy with blind-adjudication designed to evaluate the safety of uninterrupted Rivaroxaban and uninterrupted vitamin K antagonists in subjects under-going cathEter ablation for non-valvular Atrial Fibrillation) — первое проспективное рандомизированное исследование, оценивающее безопасность ривароксабана в дозе 20 мг/сут. при Катетерная аблация (КА) (с предпочтительным приемом препарата вечером накануне процедуры) по сравнению с варфарином [17]
Summary
Для составления обзора проведен поиск статей по базам данных PubMed, Scopus, Web of Science с ключевыми словами “фибрилляция предсердий”, “катетерная аблация”, “трепетание предсердий”, “антикоагулянтная терапия”, “периоперационное ведение”. Обзоры, рандомизированные исследования, действующие рекомендации, содержащие эти слова за 2010-2021гг
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