Abstract

Background: While the COVID-19 pandemic is currently impacting on health and social care in Ireland, this impact is most marked in metropolitan Dublin. This is especially the case for the Mater Misericordiae University Hospital (MMUH) in Dublin's North Inner, which is situated in an area where local socially deprived communities are at high risk of infection and of experiencing adverse outcomes. Aims: To determine baseline characteristics and longer-term care outcomes of COVID-19 patients presenting to / attending the Infectious Diseases Department at MMUH, including the virtual clinic. Methods: Retrospective study: we will retrospectively examine clinical records and extract anonymised data on patient demographics, baseline morbidity and outcomes. Prospective study: we will prospectively examine healthcare outcomes among patients who consent to follow up at two time points (three months, and six months to 12 months after discharge/onset of disease). Two patient groups will be assessed for morbid complications: those hospitalised with COVID infection and those followed-up remotely with confirmed COVID infection. Deliverables: The project will involve collaboration with Ireland's Health Service Executive (HSE) Clinical Programmes and Ireland East Hospital Group to inform health service policies that will attenuate the adverse impacts of the COVID pandemic on population health. This research protocol will evaluate morbid complications of COVID depending on the severity of the disease.

Highlights

  • W e will examine the factors that are associated with adverse initial outcomes – deaths while an in-patient, treatment in intensive care, longer hospital stays

  • Since March 2020, Ireland has experienced an outbreak of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)

  • In Ireland the median age of people infected with COVID-19 is 48, 57.2% of those infected are female, and infected persons most at risk of suffering severe illness and/or death are those over 65 years of age and those with underlying health conditions[3]

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Summary

18 Jan 2021 version 1

Any reports and responses or comments on the article can be found at the end of the article. Keywords COVID-19, coronavirus, outcome, follow-up, care, hospital care, complications, virtual clinic. W e will examine the factors that are associated with adverse initial outcomes – deaths while an in-patient, treatment in intensive care, longer hospital stays. COVID-19 infection is linked to a range of blood, cellular, and genetic abnormalities[5,7] Those most at risk of severe illness as a result of infection include elderly males and/or people with underlying health conditions (e.g. diabetes, hypertension, heart disease, malnutrition)[5,10,11]. While some patients assessed have required acute care hospitalisation, others, with milder disease, have been placed on a ‘virtual COVID community monitoring programme’ and managed in the outpatient setting. While COVID complications are likely to be more serious in those requiring hospitalisation, there is an evolving understanding that considerable morbidity can occur in those with milder disease

Introduction
Prospective interviews and follow-up
Data analysis
Institute of Medicine

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