Abstract
SummarySummaryCervical secretion from women with and without symptoms and signs of genital infection were analysed for their ability to inhibit inclusion formation of Chlamydia trachomatis in McCoy cell cultures. Of 173 cervical samples, 115 (66 per cent) had antichlamydial activity. The inhibition was concentration-dependent and the inhibitory factor had a molecular weight of < 10 000 Da and was heat labile. C. trachomatis was isolated by culture from six (3 per cent) of the 173 women. Those who were culture-positive for C. trachomatis had higher levels of antichlamydial activity than other age matched women. There was no relation between the antichlamydial activity and the antichlamydial antibody titre either in cervical secretion or in sera, as measured by micro-immunofluorescence tests and an enzyme-linked immunosorbent assay.
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