Abstract
The in vitro anticandidal and antioxidant activities of phenolic compounds detected in flower extracts of Pyrostergia venusta were investigated. One flavonoid (quercetin-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-galactopyranoside) and two phenylpropanoid glycosides (verbascoside and isoverbascoside) were purified by using the HPLC technique. The antimicrobial activity of the extracts was evaluated against five Candida strains (C. albicans, C. krusei ATCC 6258, and clinical isolates strains of Candida sp: C. albicans, C. krusei, C. tropicalis, C. parapsilosis and C. guilhermondii). The antimicrobial and antioxidant activities were confirmed in extracts. Semi-purified fraction and verbascoside showed similar activity to amphotericin B. Acknowledgements: Ouro Fino – Agribusiness
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