Anticancer Activity of Some Marine Macroalgae in Hepatocellular Carcinoma Cell Lines (HepG2)

Abstract

In the present study, overcome on liver cancer and other types of cancer by foods that have bioactive chemical components is the most important trend. The marine organisms can give us this opportunity. In this study, we collected some water samples to assess the environmental impacts on the biota existed in red sea cost. The measurements demonstrated that, the habitat was healthy and not effected by any biotic or abiotic stressors. Also, we screened some methanolic extracts of some marine macro-algae on liver cancer cell line. The results showed a good impression about Jania Rubens – red algae – has LC 50 8.61 µg/mL followed by Hydroclathrus Clathratus – brown algae – 17 µg/mL, then Sargassum Cinereum – brown algae – 18.2 µg/mL. Finally, Scinaia Fascularis , – red algae – at value 43 µg/mL. We recommend that, the isolating of the bioactive compounds extracted from these algae will be needed in traditional medicinal field.