Antibody Response to Newcastle Disease Virus and Pasteurella multocida of Two Strains of Turkeys

Abstract

The primary and secondary response to Newcastle disease virus (NCDV) and Pasteurella multocida (PM) of two turkey lines were studied following vaccinations with either NCDV or PM alone, or in combination. The two turkey strains were 1) a randombred control line (RBC1) and 2) a subline (E) of Line RBC1 selected 27 generations for increased egg production. This study consisted of five trials. Each trial represented a separate hatch. In Trial 1, poults of each line were subcutaneously vaccinated with a 1-mL dilution of B1 type LaSota strain NCDV vaccine. In Trial 2, poults of each line were wing-web vaccinated with the M-9 strain of PM Heddleston Type 3 × 4 cross at 6 and 10 wk of age. In Trial 3, poults of each line were subcutaneously vaccinated on the back of the neck with 1 mL of inactivated NCDV at 6 and 10 wk of age. In Trial 4, .5 mL of a PM bacterin containing Types 1, 3, and 4 in an oil emulsion was used to subcutaneously vaccinate poults of each line at 6 and 10 wk of age. In Trial 5, poults of each line were simultaneously vaccinated with inactivated NCDV (subcutaneously) and a PM bacterin (intramuscularly) at 6 and 10 wk of age.Line RBC1 had significantly (P<.01) higher maternal antibodies to Newcastle disease at 3 wk of age than those of Line E. The RBC1 line generally had significantly higher levels of antibodies than Line E in response to vaccination for both NCDV and PM when administered singularly or in combination.