Antibody response three months after SARS-CoV-2 infection.

Abstract

The coronavirus disease‐19 (COVID‐19) pandemic became the greatest public health challenge globally. In our study, it was aimed to determine the antibody levels in the third month after the COVID‐19 infection and the symptoms that continued until the third month from the onset of the infection. One hundred people who applied to Tarsus State Hospital with the suspicion of COVID‐19 and were positive for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection by real‐time reverse transcriptase‐polymerase chain reaction were included. We collected serum samples from individuals, who were 3 months postinfection, and tested them in anti‐SARS‐CoV‐2 Quanti‐Vac ELISA IgG kit coated with recombinant S1 antigen for testing SARS‐CoV‐2 antibodies. Antibody levels were found to be higher in those aged ≥55 years, nonsmokers, those with comorbidities, and those who were hospitalized. The four most common symptoms that individuals initially encounter; are weakness, muscle and joint pain, loss of taste and smell, and cough. In 3 months after COVID‐19 infection, the most common four symptoms are; muscle and joint pain, insomnia, fatigue, and other problems were determined. In conclusion; more research is needed to determine threshold levels of serum antibodies that could prevent reinfection of SARS‐CoV‐2.