Abstract
Immunisation of Houghton White Leghorn line 151 and 6 1 chickens with empty reticuloendotheliosis virus particles elicited a primary antibody response which is probably directed against the viral envelope glycoproteins gp 73/71 and gp22. Antibodies in line 15I birds were shown to be non-neutralising and did not protect against the tumourigenic effects of reticuloendotheliosis virus, strain T. However, immunised line 6 1 chicks did not exhibit the runting syndrome associated with reticuloendotheliosis dotheliosis virus infection, suggesting that antibody against viral coat proteins may play a role in modulating pathogenesis in certain lines of chicken.
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