Abstract
A child with classical hemophilia who had received plasma intermittently since age 8 months was found to have an antihemophilic globulin inhibitor at two years of age. The inhibitor was characterized as a gamma<sub>2</sub> kappa<sub>2</sub> IgG antibody; in addition the presence of a low molecular weight IgM antibody was also demonstrated. Immunological properties of the inhibitor are presented, and possible etiological factors and clinical management of such patients are discussed.
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