Antibody levels against Newcastle Disease Virus in chickens in Rajshahi and surrounding districts of Bangladesh

Khandoker Mohammad Mozaffor Hossain,Ichiro Yamato,Md Yamin Ali

doi:10.5539/ijb.v2n2p102

Khandoker Mohammad Mozaffor Hossain, Ichiro Yamato + Show 1 more

Open Access

https://doi.org/10.5539/ijb.v2n2p102

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Abstract

A serological survey on the prevalence of antibodies to Newcastle disease virus (NDV) was carried out in broiler and layer chickens in Rajshahi and surrounding districts of Bangladesh. A total of 960 sera samples were collected from broiler (102) and layer (90) farms during the period from January to December 2008. Haemagglutination inhibition (HI) test was performed using NDV antigen to determine antibodies against NDV. The overall seroprevalence of antibodies to NDV in broiler and layer chickens were 78.04% (510 samples) and 96.67% (450 samples), respectively. Antibody levels against NDV were recorded in different age groups for both broiler and layer chickens. Seroprevalence of antibodies to NDV was found significantly (p<0.05) higher in young (broiler 23.88%, layer 11.33%) than in adults (broiler 18.38%, layer 9.22%). Again these levels were recorded in different seasons of the year, with significantly (p<0.05) higher during summer in comparison to other seasons. The level of protection of broilers was found unsatisfactory which must be improved by hyper-immunizing the hens before laying and adopting good managemental practices, whereas, the level of protection in layers was found satisfactory.

Highlights

X (Orajaka et al, 1999)
The current vaccination schedule in Bangladesh directed by the Directorate of Livestock Services (DLS) includes administration of a live lentogenic vaccine (BCRDV) of F-strain by intra-ocular instillation to chicks followed by a live mesogenic vaccine (RDV) of M-strain by intramuscular injection at 21 days old chicks which is repeated at every six months interval
Chicks from immunized parents possess high level of maternally derived antibodies (MDA) which protect them against virulent and vaccine viruses (Allan et al, 1978 and Rahman et al, 2002)

Summary

Introduction

X (Orajaka et al, 1999). The current vaccination schedule in Bangladesh directed by the Directorate of Livestock Services (DLS) includes administration of a live lentogenic vaccine (BCRDV) of F-strain by intra-ocular instillation to chicks followed by a live mesogenic vaccine (RDV) of M-strain by intramuscular injection at 21 days old chicks which is repeated at every six months interval. A total of 510 serum samples were collected from different commercial broiler farms and were subjected to HI test. Whereas in 5-6 weeks of age HI antibody titers varied from 22 to 28 (their respective percentages were 22.45, 33.33, 20.41, 11.56, 8.84, 2.04 and 1.36) with a GMT of 5.67.

Results

Conclusion