Abstract
Very few observations have been published about the development of antibodies against gonadotropins in the human. Human FSHand hCG-antibodies have been detected in a patient with isolated FSH-deficiency after human menopausal gonadotropin administration [l], or after human menopausal (hMG) and chorionic gonadotropin (hCG) administration in women with hypopituitarism [2]. Recently, antibodies to hCG/LH have been isolated by affinity chromatography from normal human sera, initially detected in post-partum sera. and consecutively found in sera from males, non-pregnant females and children 131. The aim of this investigation was to prove the possible development of antibodies against hCG in some physiological and pathophysiological conditions as well as after application of human chorionic gonadotropin to the female.
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