Abstract
More than forty water-soluble antigens were found in the Reiter treponeme by crossed immunoelectrophoresis, using isolated and concentrated Ig from immunized rabbits. Five antigens reacted with antibodies in sera from selected patients with secondary syphilis, all having strong reactions in traditional tests for syphilis. No antibodies were found in selected healthy controls nonreactive in traditional syphilis tests. The five antigens represent available and potentially valuable antigens for development of new diagnostic syphilis tests. One of the antigens probably represents the axial filament. The findings open new possibilities for precise immunochemical studies of treponemes and of the immunology of syphilis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.