Abstract
Aspergillus and Penicillium species produce extracellular polysaccharides (EPS) of which (1→5)‐interlinked β‐D‐galactofuranosides are immunodominant. Synthetic tetra‐ and heptamers of (1→5)‐interlinked P‐D‐galactofuranosides conjugated to tetanus toxoid were used to produce antibodies in rabbits. The antibodies obtained with the tetramer conjugate reacted only with EPS of a few Penicillium and Aspergillus species. Antibodies obtained with the heptamer conjugate were reactive with EPS of all the Penicillium and Aspergillus species tested. The reaction with P. digitatum EPS could be inhibited by the synthetic heptamer of β‐(1→5) interlinked galactofuranosides. No reactions were observed with EPS of moulds belonging to any other genus.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.