Abstract
Bacterial antibiotic resistance has become an emerging global challenge. Infections that are caused by aggressive pathogens, such as Mycobacterium tuberculosis (MTB) and methicillin-resistant Staphylococcus aureus (MRSA), have increasingly become difficult to treat and there is a need to develop new antibacterial agents against problematic pathogens. In this article, we summarize the mechanisms of important antibiotic families that inhibit cell wall formation (β-lactams and vancomycin) or disrupt cell membrane (polypeptides) or inhibit fatty acids that form cell membranes. The recent development of novel antibacterial agents that target fatty acid synthesis and inhibit cell membrane formation is also discussed.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
