Abstract
The antibiotic revolution (the “domestication” of microorganisms) ranks in importance in human history with the domestication of wild animals. Its story is full of lessons for discovery, invention and innovation, not least because its two main components, penicillin and streptomycin, were found and developed in completely different ways, by quite different kinds of people. Because it all took place within a single generation, and is well documented, these lessons are very accessible. Amongst the topics on which they throw light are funding and protection of new ideas (as well as resistance to them), path dependence and research as an evolutionary process.
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