Abstract
Endophthalmitis is an uncommon but potentially devastating intraocular infection that can occur after routine cataract surgery. Prevention is of great importance because of potentially severe consequences of endophthalmitis. Various routes of administration of antibiotics have evolved, including preoperative topical, intraoperative (infusion, intracameral), and postoperative subconjunctival and topical routes. There is growing evidence that intracameral injection of antibiotics at the conclusion of surgery is an effective method of endophthalmitis prophylaxis. The intracameral route of administration is supported by randomized controlled trial data. The evidence supporting subconjunctival antibiotic prophylaxis is retrospective and less conclusive.
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