Abstract
Most emergency physicians do not prescribe antibiotics for acute asthma, and this restraint is supported by the literature. Telithromycin, one of a new class of agents called ketolides, has demonstrated immunomodulation effects in addition to antimicrobial effects, similar to the macrolides. A multinational group evaluated telithromycin for treatment of acute asthma exacerbation in an industry-sponsored, randomized, double-blind, placebo-controlled trial. A total of 278 adult patients received usual care and a 10-day course of either …
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