Antibiotics- Access or excess? Reviewing alternative targets for antibacterial activity

Abstract

Antimicrobial resistance is a condition in which microorganisms no longer respond to medications that were previously effective against them. This makes infections more difficult to cure, necessitating greater doses, and leads to increase morbidity and mortality. Antimicrobial therapy failure is frequently caused by the spread of resistant infections, which eventually replace susceptible pathogens. Antibiotics are a type of medicine employed for a limited time and for specific indications. As a result, there isn't much incentive to research and development of newer antibiotics. The temporal utility of antibiotics keeps decreasing as we use them. Hence it is a continuous ordeal, and we need new agents to fight the war against infection. This article attempts to summarize the newer anti-bacterials and some alternative approaches.