Antibiotic susceptibility patterns of bacteria isolated from patients with community acquired urinary tract infections.

Abstract

Objective: The emergence of multi-drug resistant uro-pathogenic bacteria has negatively impacted the treatment of urinary tract infections. The objective of this study was to identify the rising rates of resistance of uro-pathogenic bacteria to antimicrobials. Study Design: Retrospective Analysis of Bacteria Isolated from urine cultures of adult outpatients with complicated or long-term urinary tract infections was done. Setting: Out- patient Clinics of Independent University Hospital, An Urban Tertiary Care Teaching Hospital in Faisalabad. Period: July 2021 to July 2022. Material & Methods: Urine samples from patients advised urine cultures after presenting with symptoms of urinary tract infections were included using convenience sampling technique. Results: The most common etiologic agent isolated was E.coli, followed by Klebsiella, Pseudomonas and Staphylococcus saprophyticus. The drugs with the highest susceptibility were ciprofloxacin (56.3%), nitrofurantoin (53.1%), and imipenem (44.8%). Nalidixic acid (40.6%), sulfamethoxazole-trimethoprim (37.5%), and erythromycin (25%) had low efficacy, while penicillin G and co-amoxiclav failed to work on all bacterial isolates in this study. Conclusion: The rising rates of resistance of uro-pathogenic bacteria to multiple drugs indicate the employment of good antibiotic stewardship practices by clinicians in outpatient clinics, to decrease the burden of infections in the communities.