Abstract
Lower respiratory tract infections (LRTI) are one of the commonest health problems demanding frequent consultation and hospitalization. Unnecessary and inappropriate initial antibiotic therapy is a potentially modifiable factor that is associated with increased mortality in patients with serious infections. To study bacterial profile and susceptibility pattern of lower respiratory tract infections in a teaching hospital.Prospective study done in the department of Microbiology at Prathima Institute of Medical Sciences, Nagunuru, Karimnagar, Telangana., Tover a period of 18 months ie from January 2019 to July 2020. A total of 120 samples from respiratory tract were studied for bacterial isolates and antibiotic susceptibility. A total of 120 cases were studied. The male to female ratio was 2:1. Among the bacterial isolates, 76.6% were Gram negative bacilli and 23.3% were gram positive cocci. Among Gram negative bacteria, the predominant bacterial isolate was Klebisella. pneumoniae (45.8%) followed by Pseudomonas. aeruginosa (28.3%.)Present study, was based on the pattern of resistance to commonly used antibiotics by organisms causing lower respiratory tract infections (LRTIs) in our institute. This may help us to study the more susceptible group of drugs in our institute which would help prepare an antibiogram and develop a policy for rational antibiotic prescription.
Highlights
Lower respiratory tract infections (LRTIs) are one of the serious communicable diseases and the 3rd leading cause of death globally, after ischaemic heart and cerebrovascular diseases. 1 In developing countries management of lower respiratory tract infections (LRTIs) is difficult in both children 2 and adults, 3 especially due to the issues associated with identification of the etiological agents and selection of appropriate antibiotics
1 In developing countries management of LRTIs is difficult in both children 2 and adults, 3 especially due to the issues associated with identification of the etiological agents and selection of appropriate antibiotics
There were a total of 220 cases of suspected LRTI of which 120 were studied
Summary
Lower respiratory tract infections (LRTIs) are one of the serious communicable diseases and the 3rd leading cause of death globally, after ischaemic heart and cerebrovascular diseases. 1 In developing countries management of LRTIs is difficult in both children 2 and adults, 3 especially due to the issues associated with identification of the etiological agents and selection of appropriate antibiotics. Aim of the study: To study bacterial profile and susceptibility pattern of lower respiratory tract infections in a teaching hospital. A total of 120 samples from respiratory tract were studied for bacterial isolates and antibiotic susceptibility. Aeruginosa (28.3%.) Conclusion: Present study, was based on the pattern of resistance to commonly used antibiotics by organisms causing lower respiratory tract infections (LRTIs) in our institute. Among Gram negative bacteria, the predominant bacterial isolate was Klebisella. This may help us to study the more susceptible group of drugs in our institute which would help prepare an antibiogram and develop a policy for rational antibiotic prescription
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