Abstract

Organisms of the genus Bacillus are aerobic, sporeforming, usually gram-positive rods which, with the exception of Bacillus anthracis, have been implicated infrequently in human disease. These organisms are ubiquitous and commonly occur as contaminants in cultures of clinical material. However, well-documented cases of disseminated infection with these organisms in man have been described [1-3]. Recently, we observed a fatal case of pneumonia and bacteremia due to Bacillus cereus in a patient with subacute lymphocytic leukemia. Lack of information on the susceptibility of Bacillus species to antimicrobial agents was a handicap in treating this patient. Patients with markedly impaired host resistance are now frequently encountered, and information on the antimicrobial susceptibility of non-pathogenic bacteria that may infect these patients is desirable. For this reason, the in-vitro susceptibilities to selected antibiotics of 49 strains representing six species of Bacillus were studied.

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