Abstract
Background: Antibiotic surveillance in hospital settings is mandatory for optimal antibiotic therapy for the patient. Only a small number of studies have focused on antibiotic surveillance in hospitalized newborns, infants, and children. Objectives: The goal was to evaluate antibiotic use in our Pediatric Intensive Care Unit (PICU) and evaluate it for a possible association with the length of PICU stay. Methods: A retrospective, observational, cohort study was conducted from January 2015 to April 2017, involving subjects who were hospitalized in the PICU at Sanglah Hospital. The inclusion criteria were children aged between 1-month-12-years old, who had a blood culture and antibiotic sensitivity test result in their medical record. The exclusion criteria were incomplete medical records, blood cultures showing 2 types of bacteria at the same time (gram-positive and negative), or contaminated blood results. Factors associated with mortality were analyzed using a Chi-square test, with p < 0.05 considered to be statistically significant and the Risk Ratio (RR) of the associated factors was determined by 95% CI. Results: Multivariate analysis showed that the significant predictors of PICU length of stay were the appropriate continuation of antibiotics (RR 1.19; 95% CI 1.043 to 1.373; P = 0.047). There were also significant results for antibiotic compatibility and length of stay (RR 3.6; 95% CI 0.869 to 15.428; P = 0.049). Conclusion: Appropriate continuation of antibiotics and the compatibility of continuation antibiotics were significant predictors of length of PICU stay based on multivariate analysis.
Highlights
Antibiotics are commonly used in the hospital settings, especially in the pediatric intensive care unit
Appropriate continuation of antibiotics and the compatibility of continuation antibiotics were significant predictors of length of Pediatric Intensive Care Unit (PICU) stay based on multivariate analysis
The 12-year age limit was used because Sanglah Hospital policy stipulates that patients’ ≤12 years of age are to be treated in the PICU
Summary
Antibiotics are commonly used in the hospital settings, especially in the pediatric intensive care unit. Antibiotic Surveillance in the Pediatric Intensive Care Unit (PICU). Similar results were reported by Briassoulis et al [6] who did a cohort study on the use of antibiotics. They found that as many as 67.2% of PICU patients received antibiotics on the first day of treatment and 80.5% received at least one antibiotic during PICU treatment. Antibiotic surveillance in hospital settings is mandatory for optimal antibiotic therapy for the patient. A small number of studies have focused on antibiotic surveillance in hospitalized newborns, infants, and children
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
