Abstract
Overuse of antibiotics has attracted increasing concerns globally. Excessive use of antibiotics is believed to be associated with the development of antimicrobial resistance, which can seriously jeopardise health-care services and patient outcomes. 1 Zhang X Cui Y Liu C Zuo K Tang Y Antibiotic sales in primary care in Hubei province, China: An Analysis of 2012–2017 Procurement Records. Int J Environ Res Public Health. 2019; 163376 Crossref Scopus (12) Google Scholar An Article by Houyu Zhao and colleagues 2 Zhao H Wei L Li H et al. Appropriateness of antibiotic prescriptions in ambulatory care in China: a nationwide descriptive database study. Lancet Infect Dis. 2021; (published online Jan 27.)https://doi.org/10.1016/S1473-3099(20)30596-X Summary Full Text Full Text PDF Scopus (12) Google Scholar —one of the largest studies ever conducted in China—published by The Lancet Infectious Diseases, revealed a concerningly high proportion of inappropriate prescriptions of antibiotics. More than 51% of antibiotic prescriptions (almost 2 million per year) from 139 public hospitals for outpatient visits were found to be inappropriate, compared with 15·3% that were deemed appropriate. China has 12 436 secondary and tertiary hospitals. 3 National Health Commission of the People's Repubic of China2019 health development report. http://www.nhc.gov.cn/wjw/nianb/list.shtmlDate: 2020 Date accessed: July 15, 2020 Google Scholar The total volume of inappropriate antibiotic prescriptions from secondary and tertiary hospitals could have exceeded 173 millions per year on the basis of these data. Appropriateness of antibiotic prescriptions in ambulatory care in China: a nationwide descriptive database studyInappropriate antibiotic prescribing was highly prevalent nationwide in China. Over half of the antibiotic prescriptions were inappropriate in secondary-level and tertiary-level hospitals, suggesting an urgent need for outpatient antibiotic stewardship aimed at optimising antibiotic prescribing to achieve the goals set in China's 2016 national action plan to contain antimicrobial resistance. Full-Text PDF
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