Abstract

Due to their inappropriate and indiscriminate use in treating mastitis, most antibiotics are now ineffective. The aim of the study was to determine the antibiotic sensitivity profile of identified bovine mastitis pathogens. Twenty-seven out of 38 isolates were revived from a previous work and were identified for antibiotic sensitivity. Gram-negative isolates were Klebsiella pneumoniae, Brevundimonas diminuta, Escherichia coli, Acinetobacter baumanii, Vibrio metschnikovii, Flavimonas oryzihabitans and Pantoea agglomerans. Gram-positive isolates were Streptococcus agalactiae, Lactococcus lactis, Streptococcus sp. group C or G, and Corynebacterium renale. Enterobacteriaceae isolates were resistant to Beta lactams, Erythromycin, Nitrofurantoin, Novobiocin, and Clindamycin but were sensitive to Fluroquinones. Miscellaneous Gram-negative isolates were sensitive to Colistin and Ofloxacin but were resistant to Beta lactams, Novobiocin, and Clindamycin. Str. agalactiae isolates were sensitive to Cefaclor, Ofloxacin, and Gentamicin but were resistant to Cloxacillin and Trimethoprim. Gram-positive isolates were sensitive to Oxytetracycline, Ofloxacin, Erythromycin, and Gentamicin. Mastitis treatment guided by antibiotic sensitivity testing is a promising course of therapy likely to succeed. The regimen can be further improved by a combination of non-antibiotic therapeutic methods, responsible use of suitable antibiotics, good sanitation protocols, and organized recording of data.

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