Abstract
Microbial infections are frequently occurring worldwide due to the presence of antibiotic-resistant genes in the environment. Antibiotics are becoming ineffective in the treatment of diseases due to the resistance in bacterial pathogens against these drugs. Recently, there is an incredible challenge for researchers and medical professionals in the treatment of these infectious diseases. In this study, water samples were collected from the junction of river and untreated municipal sewage water and inoculated in an antibiotic supplemented growth medium. The four isolates have been found to be ampicillin-resistant (Klebsiella pneumoniae strain AU06, Pseudomonas aeruginosa strain AU07, Aeromonas hydrophila strain AU02, and Acinetobacter baumannii strain AU01) while two isolates as erythromycin-resistant (Streptococcus pneumoniae strain AU09 and Enterococcus faecalis strain AU05). These isolates harboured beta-lactamase and ermB methylase gene conferring resistance to the bacteria. The study suggests an urgent need to stop the entry of untreated sewage water into the river to avert serious health-related issues.
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