Abstract
Resume. The aim of the study was to highlight the causes of antibiotic resistance, rational antibiotic therapy and the role of probiotics in the complex treatment of peritonitis.
 Matherials and methods. In 2021, surgical interventions were performed on 360 patients with acute peritonitis of various genesis in the surgical department of the Brovary Multidisciplinary Clinical Hospital. The distribution of patients by gender was as follows: 174 (48.3%) men and 186 (51.7%) women.
 Results. 391 strains of microorganisms belonging to facultatively anaerobic and aerobic gram-negative and gram-positive pathogens were isolated from the patients, including: Escherichia coli – 144 (36.8%) strains, Enterococcus faecalis – 47 (12.0%), Streptococcus spp. – 52 (13.3%), Staphylococcus aureus – 37 (9.5%), Staphylocooccus haemolyticus – 23 (5.9%), Klebsiella pneumoniae – 31 (7.9%), Citrobacter – 25 (6.4% ), Acinetobacter baumannii – 13 (3.3%), Pseudomonas aeruginosa – 14 (3.6%), Proteus mirabilis – 5 (1.3%) strains. In most cases, microbial associations of two, three, and four microorganisms that showed high antibiotic resistance were sown.
 Conclusions. In order to overcome antibiotic resistance, it is necessary to clearly define the indications and follow the principles of rational antibiotic therapy. Probiotic solutions are effective for the rehabilitation of the abdominal cavity with peritonitis, which has been proven by experimental research and opens a new era in the treatment of peritonitis.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
