Abstract

Hospital-acquired infections with Staphylococcus aureus have increased over the years and the rise in incidence has been accompanied by a rise in antibiotic-resistant strains notably methicillin-resistant S. aureus (MRSA) and more recently vancomycin-resistant strains. In order to have adequate information for treatment of infections caused by S. aureus, it is important to understand trends in the antibiotic-resistance patterns as well as diversity of strains across geographical regions.

Highlights

  • Hospital-acquired infections with Staphylococcus aureus have increased over the years and the rise in incidence has been accompanied by a rise in antibiotic-resistant strains notably methicillin-resistant S. aureus (MRSA) and more recently vancomycin-resistant strains

  • A rise in panton valentine leukocidin (PVL)-positive S. aureus strains in Africa is of great concern as this could promote the emergence of highly virulent strains

  • The continuous surveillance of antibiotic resistance in S. aureus is important to prevent the spread of multidrug resistant strains

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Summary

Introduction

Hospital-acquired infections with Staphylococcus aureus have increased over the years and the rise in incidence has been accompanied by a rise in antibiotic-resistant strains notably methicillin-resistant S. aureus (MRSA) and more recently vancomycin-resistant strains. In order to have adequate information for treatment of infections caused by S. aureus, it is important to understand trends in the antibiotic-resistance patterns as well as diversity of strains across geographical regions

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