Abstract
A total of 85 samples were collected from moribund birds with different pathological conditions like perihepatitis, enteritis, air sacculitis and pneumonia. In this investigation thirty two avian pathogenic Escherichia coli (APEC) strains isolated from broiler chickens with colisepticemia and examined for susceptibility to antimicrobials of veterinary and human significance. Serotyping of these isolates revealed 32 ‘O’ serotypes, predominantly O11, O79 and O111 accounting for 26.15 %. The percentage of other serotypes varied from 1.54-4.61 %. In vitro antibiotic activities of 20 antibiotic substances against the isolates were determined by disc diffusion test (Kirby Bauer method). Multiple resistances to antibiotics were observed in all the isolates. Antibiogram profiles indicated maximum resistance to Nitrofurazone (90.77 %), followed by tetracycline (83.08 %) & cotrimoxazole(76.92 %). High sensitivity to ciprocloxacin and enrofloxacin (83.08 %), chloramphenicol (81.54 %), pefloxacin (76.92 %) and norfloxacin (75.39 %) were noticed.
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