Abstract
Urinary tract infections (UTIs) are one of the most common infection in children in Syria. This study was conducted on 48 urine samples from pediatric UTI patients aged from 0 days to 18 years. The ratio female/male UTI patients was 4:1. Escherichia coli was the first cause of UTIs in childhood (63%), followed by Klebsiella pneumonia (25%). A high rate of resistance (≥ 20%) to twelve antibiotics was observed among isolated urine bacteria, while only three antibiotics showed a rate of resistance below 20%. A good in vitro antibacterial activity was observed for amikacin, imipenem and gentamycin against isolated urine bacteria. First and second generation cephalosporins, aminoglycosides, fluoroquinolones, trimethoprim-sulfamethoxazole and other agents displayed moderate to high resistance rates and multi-antibiotic resistance was found as well. 98% of urine bacteria isolates were resistant to at least two antibiotics. Our results suggest that the antibiotic susceptibility may vary according to the bacterial infection types, since the comparison of susceptibility between Escherichia coli and Klebsiella pneumonia showed a difference of resistance rates.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.