Abstract

The aim of this study was to determine the antibiotic resistance of Salmonella strains isolated from poultry products from Bamako's markets and slaughter areas. It involved the analysis of 64 Salmonella strains isolated from poultry eggs and organs. The antibiotypic profile of these strains was determined using the Kirby-Bauer agar diffusion method and the recommendations of the Comité de l'antibiogramme de la société française de microbiologie (CA-SFM). This work resulted in high rates of resistance to imipenem (93.75%), followed by kanamycin (84.37%) and doxycycline (67.18%). In addition, low levels of resistance were observed to gentamicin (12.5%) and flumequine (26.56%). Sequencing of the complete genome of the isolated strains and the use of bioinformatics tools made it possible to obtain certain genes conferring antibiotic resistance, namely marB, marA, marC, marR, mdtG, mdtQ, folA, ksgA, rarD and STM169. Some of these genes are multi-resistant to antibiotics (marB, marA, marC).

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