Abstract

Pharmaceutical sector of Syrian Arab Republic before the war was characterized by bold and successful development since the late 1980s. With the beginning of war in the country back in March 2011, momentum has changed significantly. Traumatism, communicable diseases related to morbidity and mortality as well as wound infections became particularly hot public health concern. This relates not only to the direct victims of military conflict but also to the displaced civilians, refugees, and ordinary citizens alike. Evolving legislative framework in Syria since 1980s tolerated dispensing of antibiotics without appropriate prescription. Such practice led to spreading of antibiotic resistance among the local bacteria frequently causing both community-acquired and nosocomial infections. Laboratory findings of resistant bacteria strains among the Syrian refugees in some European countries serve as evidence of concern spreading far beyond Middle East. Practice of self-diagnosis and self-medication with antibiotics by patients themselves and restraint to pharmacist advice is widespread. A number of recommendations is presented to stakeholders to compact antibiotic resistance after the peace is established in the country. The successful implementation of such recommendations is the way to preserve shrinking golden reserve of highly potent antibiotics as it is the last defense line against resistant bacterial strains causing severe life—threatening infections.

Highlights

  • Specialty section: This article was submitted to Health Economics, a section of the journal Frontiers in Public Health

  • Evolving legislative framework in Syria since 1980s tolerated dispensing of antibiotics without appropriate prescription. Such practice led to spreading of antibiotic resistance among the local bacteria frequently causing both community-acquired and nosocomial infections

  • Laboratory findings of resistant bacteria strains among the Syrian refugees in some European countries serve as evidence of concern spreading far beyond Middle East

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Summary

Antibiotic Resistance in Syria

Middle East presents a distinctively different region of the Old World [6]. Ninety year old historical records on practice of pharmacy in Syria describe it as a former Ottoman province under French mandate. Since 1998, patients have had to pay little charges to get access to certain health services in some public hospitals [9]. Threatened supplies of essential medicines is currently the case even far outside major refugee migration routes [22] and war torn areas of the country. Major multilateral agencies such as the Médecins Sans Frontières (MSF) have claimed serious degree of disrupted access to basic health care for the ordinary citizens. Official WHO estimate was that Syria needed a total of $900 million worth of essential medicines and supplies in a single year following March 2013. Consequences were striking in some clinical areas such as diabetes, cancer care, appropriate blood storage and testing facilities necessary for safe transfusions in surgery [22]

RESISTANCE IN SYRIA
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