Abstract
This review article focuses on the essential topic of antibiotic resistance, a growing global health threat that calls into question the efficacy of previously effective therapies. It starts by recognizing the enormous influence that antibiotics, which were discovered in the 20th century, have had on medicine. Despite their effectiveness in treating infections, these medications' overuse and abuse have had unforeseen repercussions. Pathogens have evolved a number of defense mechanisms against antibiotics as their usage in human healthcare, agriculture, and animal husbandry has increased. This resistance extends throughout communities and the environment in addition to occurring in clinical settings. The paper emphasizes how environmental variables, agricultural runoff, and other microbes can all contribute to the acquisition of resistance genes. It highlights how gene transfer contributes to the rapid proliferation of resistant strains. The worldwide nature of travel and trade adds to the complexity of this problem by making it easier for resistant germs to spread across national boundaries. Many antibiotics could become ineffective as a result of this resistance crisis, which would raise healthcare expenses, lengthen hospital stays, and raise mortality rates. The essay emphasizes the necessity of a multipronged strategy, including improved antibiotic stewardship, surveillance initiatives, and public education, to counter this threat. It urges cooperation between researchers, legislators, and healthcare professionals in order to create novel remedies and encourage the prudent use of antibiotics. In order to protect public health for future generations, the review intends to increase awareness and motivate action against the spread of antibiotic resistance by addressing these interrelated issues.
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