ANTIBIOTIC PROPHYLACTICS ON CURETTAGE FOR PREVENTING PELVIC INFLAMMATORY DISEASE EVENTS: IS IT NECESSARY?

Fauna Herawati,Dwi Handayani,Rika Yulia,Abdul Rahem

doi:10.22159/ajpcr.2018.v11i11.27817

Abstract

Objective: This study aimed to compare pelvic inflammatory disease (PID) symptoms in curettage procedure with three antibiotic prophylaxis strategies.Methods: The patients were allocated to three Groups (A, B, and C). Group A was patients receiving prophylactic antibiotics and post-curettage antibiotics, Group B received prophylactic antibiotics without post-curettage antibiotics, and Group C did not receive prophylactic antibiotics but received post-curettage antibiotics. The outcomes measured to identify the occurrence of PID symptoms included leukocytes, erythrocyte sedimentation rate, temperature, pain, vaginal discharge, and bleeding.Results: This study shows that there were no significant differences in any PID symptoms between antibiotic strategies except for pain scale (p=0.03).Conclusion: The PID symptoms between the three strategies of antibiotic prophylaxis were similar.

Highlights

The antibiotic discovery is confine [1], but there is an abundant use of antibiotics occur at community [2] and at the hospital [3,4]
From May 2015 to July 2016, there were 60 subjects who met study criteria and were classified into three groups: Asian J Pharm Clin Res, Vol 11, Issue 11, 2018, 267-269 (i) Group A was a group of patients who received 1 × 2 g of prophylactic antibiotic cefazolin injection and 3 × 500 mg of post-antibiotic amoxicillin, (ii) Group B was a group of patients who received 1 × 2 g of prophylactic antibiotic cefazolin injection without post-antibiotics, and (iii) Group C was a group of patients who did not receive prophylactic antibiotics but received 3 × 500 mg of post-antibiotic amoxicillin
PKU Muhammadiyah Hospital does not have any antibiotic guidelines for the curettage procedure, even though antibiotics are always given to the patient

Summary

Introduction

The antibiotic discovery is confine [1], but there is an abundant use of antibiotics occur at community [2] and at the hospital [3,4]. The perspective database (Premier Inc., Charlotte, NC), a voluntary database that captures data from >500 acute-care hospitals from throughout the United States, was used to analyze antibiotic use in women who underwent inpatient or outpatient gynecologic surgery between 2003 and the first quarter of 2010. The database analysis result shows that antibiotics are increasingly being administered to women who underwent gynecologic surgery from 88.0% in 2003 to 90.7% in 2010 (p

Methods

Results

Conclusion