Abstract

Non-union infected bone is a chronic impairment disorder that causes severe complications for surgeons. In Pakistan a very limited literature was produced in recent years to evaluate the role of antibiotic impregnated cemented nail in infected non-union of tibia. To fill this gap this prospective study was designed to investigate the role of antibiotic Cement Coated Nailing in Infected Nonunion of Tibia in the Orthopedic Department of Liaqat University of medical and health science, Jamshoro, Pakistan, from February 2019 to February 2020. A total of 30 patients with infected "nonunion of the tibia" was enrolled during the research period. Patients within the age range of 22-61 years were part of this research. For surgery, polymer beads were added into the 40 gm cement which was prepared by adding 2 gm vancomycin and 2 gm teicoplanin. After that endotracheal tube was cut by a surgical knife to recover antibiotic and cement coated k nail. The nail was then inserted into the tibia. Resuts demonstrate that in 28 patients 93% utilization of antibodies cement coated nails helped to eradicate the infection. 24 patients achieved complete bone unification without any need for further procedure. The overall ratio of single-time antibiotic cement coated nail was observed as 70%. The infected nonunion tibia can be effectively treated if the protocol of debridement is correctly followed. Results demonstrate that bone stability can be regained with 22 to 44 weeks. We concluded that antibiotic-impregnated cemented nail is an ideal procedure to control the postoperative infection and achieve reunion.

Highlights

  • Non-union infected bone is a chronic impairment disorder that causes severe complications for surgeons

  • The infected nonunion tibia can be effectively treated if the protocol of debridement is correctly followed

  • We concluded that antibiotic-impregnated cemented nail is an ideal procedure to control the postoperative infection and achieve reunion

Read more

Summary

Introduction

Non-union infected bone is a chronic impairment disorder that causes severe complications for surgeons. The management of these chronic non-union infections may affect the healthcare department by demanding high cost and long time- effective treatment [1]. The formation of biofilm is a major source of infection These biofilms are comprised of polysaccharides and protein. The principles are based on the complete investigation of surgical debridement, stabilization of fracture, soft tissue coverage, and analysis of antibiotics level to eradicate infection. These principles are helpful to cure biofilm infections and must be observed during clinical evaluation [4]

Methods
Results
Discussion
Conclusion
Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call