Abstract
Psychiatric side effects, including mania, associated with the use of antibiotics have been reported in the research literature. Among the antibiotics, the macrolide clarithromycin, two fluoroquinolones (ofloxacin and ciprofloxacin), and the beta‐lactam penicillins have all been implicated. While the neuropharmacological mechanisms of such side effects are not clear, the primary hypothesis is that these antibiotics antagonize post‐synaptic gamma aminobutyric acid (GABA) receptors, resulting in increased neuronal excitability.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
