Abstract
Aim: The aim of the present work was to ascertain the bacterial flora causing pyometra in female dogs and their antibiotic sensitivity. Materials and Methods: A study was conducted to determine the antibiogram of bacterial species isolated from 20 female dogs diagnosed with pyometra. The vaginal discharge was collected by sterile swab and streaked smoothly over Mueller Hinton medium and sensitivity towards antibiotics was determined by measuring the zone of inhibition using a Hi-media scale. Results: The antobiogram showed that Gentamicin was the most sensitive (85%) antibiotic followed by Enrofloxacin, Ciprofloxacin and Amoxicillin (65%, 65% and 55%), respectively. The isolates were most resistant to Oxytetracycline (85%) followed by Tetracycline, Ampicillin, Chloramphenicol, Cloxacillin and Erythromycin (80%, 80%, 75%, 70% and 70%), respectively. Conclusion: Gentamicin was found to be most effective antibiotic against the bacterial species isolated from canine pyometra.
Highlights
Canine pyometra, known as cystic endometrial hyperplasia complex, is a disease of the adult dog with inflammation of the uterus and accumulation of pus, and normally occurs in the luteal phase of the oestrous cycle
The antibiogram of 20 vaginal discharge showed that Gentamicin (85%) was the most sensitive antibiotic followed by Enrofloxacin (65%)
The isolates were most resistant to Oxytetracycline (85%), Tetracycline (80%), Ampicillin (80%), Chloramphenicol (75%) Cloxacillin (70%) and Erythromycin (70%)
Summary
Known as cystic endometrial hyperplasia complex, is a disease of the adult dog with inflammation of the uterus and accumulation of pus, and normally occurs in the luteal phase of the oestrous cycle. Pyometra refers to uterine infection that occurs when contaminating bacteria overcome the normal uterine protective mechanisms. The bacterial infection is a secondary condition. Bacteria ascend through the cervix and into the uterus during oestrous. Bitches with cystic endometrial hyperplasia, seem to be incapable of eliminating bacteria that can survive in the cystic fluid. The toxic state affects the function of several organs like bone marrow, kidney, liver etc. The toxic state affects the function of several organs like bone marrow, kidney, liver etc. [1]
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