Antibiogram and multidrug resistance patterns of Staphylococcus aureus (MDRSA) associated with post operative wound infections in Basrah - Iraq

Abstract

Fifty two clinical samples collected from patients with postoperative wound infections in various age groups were examined for presence of multidrugs resistant bacteria pathogens in especially Staphylococcus aureus. The majority of samples were for age between 31 to 40 year (32.69%) followed by other age groups, while the lowest samples were taken from age group 1 to 10 year (5.76%) P<0.05. One hundred and thirty one isolates were identify and the main causative agents was S. aureus (24 isolates 18.32%), while other bacterial types isolated from postoperative wounds were as follow: Escherichia coli 16 ( 12.21%) , Klebsiella spp. 11 ( 8.39%), Enterobacter cloaeca 8 (6.1%), Proteus spp. 7 (5.34%), Pseudomonas aeruginosa 20 (15.26%), Staphylococcus epidermidis 11( 8.39%), Staphylococcus saprophyticus 8 (6.1%), Staphylococcus xylosus 5 (3.81%), Viridance streptococci 10 (7.63%), Streptococcus pyogenes 7 ( 5.34%) and Enterococcus faecalis 4 (3.05%) P<0.01. Sixteen antibiotics were used to test the resistance of S. aureus. Penicillin G gave 100% resistance ratio for all of 24 tested isolates, while the highly affected antibiotic was cefotaxime that gave the lowest resistance percentage (16.66%), other antibiotics had ranges of resistance between these limits P<0.01 . S. aureus develop a resistance mode for at least eight antibiotics. The biggest percentage of resistance was for the resistance of four antibiotics (21.18%) P<0.01. Key words: Staphylococcus aureus MDRSA, postoperative wound infections.