Abstract
Relevance. Streptococcus group B (GBS), Streptococcus agalactiae, are the causative agents of severe infections of the fetus and newborn child.
 The aim of the study was to investigate the efficacy and safety of antibacterial therapy with the use of amoxicillin with clavulanic acid and josamycin pregnant women with GBS, as well as the impact of antibiotic therapy on perinatal outcomes.
 Materials and methods. For isolation and identification of Streptococcus and Ureaplasma used bacteriological method of research. The article presents the results of a survey of 99 pregnant women, the urogenital tract, which are colonized by streptococcus group B (GBS) and Ureaplasma, during their pregnancy, delivery and perinatal outcomes.
 Results. All women were divided into three groups: I group — 29 (29.3%) women, with the presence of GBS in the urogenital tract and treated during pregnancy amoxicillin with clavulanic acid, group II — 24 (24,2%) women with the presence of GBS and Ureaplasma treated during pregnancy josamycin, group III — 46 (46.5%) of women with available GBS, which antibacterial therapy during pregnancy was not conducted. Our results confirmed the data of foreign authors about the high frequency of complications of pregnancy and delivery in women colonized by Streptococcus group B who did not receive antibiotic therapy. Thus it often happened GBS colonization of the skin and mucous membranes of infants, develop in utero infection in children born to these mothers.
 Conclusion. Upon detection of GBS in the urogenital tract of pregnant women is necessary to carry out antibacterial therapy for the prevention of complications of pregnancy, delivery and intrauterine infection of the fetus. Moreover, in the simultaneous detection of Streptococcus group B and Ureaplasma effective to schedule josamycin (wilprafen), which acts on both of the microorganism.
Highlights
The article presents the results of a survey of 99 pregnant women, the urogenital tract, which are colonized by streptococcus group B (GBS) and Ureaplasma, during their pregnancy, delivery and perinatal outcomes
All women were divided into three groups: I group — 29 (29.3%) women, with the presence of GBS in the urogenital tract and treated during pregnancy amoxicillin with clavulanic acid, group II — 24 (24,2%) women with the presence of GBS and Ureaplasma treated during pregnancy josamycin, group III — 46 (46.5%) of women with available GBS, which antibacterial therapy during pregnancy was not conducted
Our results confirmed the data of foreign authors about the high frequency of complications of pregnancy and delivery in women colonized by Streptococcus group B who
Summary
Целью исследования явилось изучение эффективности и безопасности антибактериальной терапии с использованием амоксициллина с клавулановой кислотой и джозамицина у беременных женщин с наличием СГВ, а также влияния антибактериальной терапии на перинатальные исходы. В статье представлены результаты обследования 99 беременных женщин, урогенитальный тракт которых был колонизирован СГВ и уреаплазмами, течение их беременности, родов и перинатальные исходы. Полученные результаты подтвердили данные зарубежных авторов о высокой частоте осложнений течения беременности и родов у женщин, колонизированных стрептококками группы В, не получавших антибактериальную терапию. При обнаружении СГВ в мочеполовых путях беременных необходимо проводить антибактериальную терапию для профилактики осложнений беременности, родов и внутриутробного инфицирования плода. ■ Ключевые слова: стрептококки группы В; беременность; осложнения беременности и родов; перинатальные исходы; антибактериальная терапия; амоксициллин; джозамицин
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
