Abstract

The antimicrobial activity of methanol extracts of three thalloid liverworts, Marchantia polymorpha, Conocephalum conicum and Pellia endiviifolia and bis-bibenzyl marchantin A, the most dominant compound in the methanol extract of M. polymorpha, have been investigated in this research. 1H-NMR spectroscopy revealed that the M. polymorpha and P. endiviifolia extracts of liverwort contain terpenes, oils, sugars and bis-bibenzyls, while these specific macrocyclic compounds were absent in the C. conicum extract. The antimicrobial potential was tested on eight bacterial strains. Antimicrobial effects of extracts and marchantin A were observed against Gram-positive bacteria, while they showed no effect against Gram-negative bacteria in both methods used ? well diffusion and broth microdilution.

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