Abstract
Currently, the development of biomaterials has focused on having a low Young’s modulus, biocompatibility, corrosion resistance, and antibacterial properties. Ti–Nb alloys have higher research value due to their excellent corrosion resistance and low Young’s modulus. In recent years, the antibacterial properties of materials have been enhanced by the addition of Ag and Cu. Therefore, the corrosion resistance and antibacterial properties of the Ti–12Nb–1Ag alloy formulated in the current study were investigated and compared to those of commonly used Ti alloys, G2 pure Ti (ASTM B348 CP Grade 2), and Ti–6Al–4V, via electrochemical and E. coli antibacterial tests. Meanwhile, we also carried out a microstructural analysis to investigate the composition of the alloy. The results were as follows: (1) The electrochemical test demonstrated that Ti–12Nb–1Ag had a higher corrosion resistance than Ti–6Al–4V, which is similar to the properties of pure Ti. (2) The E. coli antibacterial test demonstrated that the sterilization rate of Ti–12Nb–1Ag was higher than that of the Ti–6Al–4V alloy and pure Ti. (3) The microstructural analysis revealed that Ti–12Nb–1Ag had an acicular martensite structure, with nano-Ag precipitates observed. Based on the results of the E. coli antibacterial test and the principles of sterilization of nano-precipitates and Ag, we inferred that the nano-Ag precipitates of Ti–12Nb–1Ag enhanced the antibacterial properties of the newly developed biomaterial, which is, namely, the Ti–12Nb–1Ag alloy.
Highlights
Pure Ti and Ti alloys are two of the most popular biomaterials in use today due to their favorable properties, such as biocompatibility, mechanical properties, and corrosion resistance [1,2,3].These alloys have a considerably wide range of biomedical applications, such as dental implants, crowns, and bridges; orthodontic wires; bone plates; hip joints; and spinal fixation devices [4,5].These alloys have higher corrosion resistance and biocompatibility compared with stainless steel (e.g., 316 L and 304), which is widely used in the field of biomaterials [6,7,8]
G2 pure Ti and Ti–6Al–4V were 3.33 × 106 and 3.29 × 106, which were similar to the control group
Ti–Nb alloys have been widely used in the medical field bacterial infection and metal ion release [49]
Summary
Pure Ti and Ti alloys are two of the most popular biomaterials in use today due to their favorable properties, such as biocompatibility, mechanical properties, and corrosion resistance [1,2,3] These alloys have a considerably wide range of biomedical applications, such as dental implants, crowns, and bridges; orthodontic wires; bone plates; hip joints; and spinal fixation devices [4,5]. These alloys have higher corrosion resistance and biocompatibility compared with stainless steel (e.g., 316 L and 304), which is widely used in the field of biomaterials [6,7,8]. New Ti alloys need to be developed to replace the existing
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