Abstract

The antimicrobial effectiveness of three soft contact lens disinfection solutions widely available in Nigeria was evaluated against nine bacteria (Staphybcoccus aureus, Pseudomonas aeruginosa, Staphylococcus spp, Bacillus spp, Serratia spp, Proteus spp, Aeromonas spp, Micrococcus spp and Enterococcus spp) isolated from patients' lenses, eye swabs, lens cases and storage solutions. The disinfectants included hydrogen peroxide (Oxysept, Allergan), tris (2-hydroxyethyl) tallow ammonium chloride thimerosal (Hydrocare, Pilkington Barnes Hind) and polyaminopropyl biguanide-Dymed (#ReNu, Bausch & Lomb). The study demonstrated that all three disinfectants are capable of controlling microbial contaminations if used many months before expiration at regular concentration. Although disinfectants showed increased bacteriocidal activities with a prolonged exposure to the disinfectants, their efficacies declined rapidly when used one month prior to expiration.

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