Abstract
BackgroundProper hand hygiene with soap and detergents prevents the transmission of many infectious diseases. However, commercial detergents are less likely to be accessible or affordable to poor people in remote rural areas. These people traditionally use some plant parts as a detergent even though their antibacterial activity has not been yet investigated. Therefore, this study aims to determine the antibacterial activities of some of the plants against bacteria isolated from humans.MethodsPlants selected for this study are Phytolacca dodecandra fruits, Rumex nepalensis leaves, Grewia ferruginea bark and leaves. The samples of these plants were collected from rural areas of Jimma town based on their ethno-botanical survey and information on their local use. Acetone was used as a solvent to extract the bioactive constituents of the plants. The antibacterial activities of the plants were evaluated against reference strains and bacteria isolated from humans using disc diffusion and macro dilution methods.ResultsThe plant extracts have shown varying antimicrobial activities against the bacterial species tested. Susceptibility testing shows zones of inhibition ranging from 8.0 ± 1.0 mm to 20.7 ± 5.5 mm. The MIC and MBC of the plants against the bacterial species tested were 3.13 and 12.5 mg/ml respectively. These variations are attributed to different concentrations of the bioactive constituents of the extracts like saponins, tannins, flavonoids and terpenoids.ConclusionThe studied plants can contribute to achieve better personal hygiene since they are effective against different bacterial agents and are freely available in rural areas.
Highlights
Proper hand hygiene with soap and detergents prevents the transmission of many infectious diseases
The extract yields of the plants and their phytochemical constituents The method used for the extraction achieved varying extract yields ranging from 6.40 g to 15.47 g (Table 2)
Variations were observed in the concentration of the phytochemical constituents of the plant parts and species
Summary
Proper hand hygiene with soap and detergents prevents the transmission of many infectious diseases. Commercial detergents are less likely to be accessible or affordable to poor people in remote rural areas. These people traditionally use some plant parts as a detergent even though their antibacterial activity has not been yet investigated. Soap has been used for personal hygiene for many centuries. Hands perform several activities through which they come into contact with contaminated objects. Hands will be routes for disease transmission if proper hand hygiene is not performed. Many infectious diseases are transmitted through hand contacts from the immediate environment [3, 4].
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