Antibacterial effects of silver-zirconia composite coatings using pulsed laser deposition onto 316L SS for bio implants.

G Pradhaban,Gobi Saravanan Kaliaraj,Vinita Vishwakarma

doi:10.1007/s40204-014-0028-5

G Pradhaban, Gobi Saravanan Kaliaraj + Show 1 more

Open Access

https://doi.org/10.1007/s40204-014-0028-5

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Abstract

Bacterial invasion on biomedical implants is a challenging task for long-term and permanent implant fixations. Prevention of initial bacterial adherence on metallic implants is an important concern to avoid extracellular matrix (biofilm) secretion from bacteria that is resistant to antibacterial agents. In order to overcome this defect, recently, surface coatings such as zirconia (ZrO2) with higher smoothness have been shown to improve implants durability. In the present study, pulsed laser deposition (PLD) was used to deposit ZrO2 and silver (Ag)-ZrO2 composite coatings onto 316L stainless steel (316L SS). Phase purity, surface roughness and surface morphology, thickness of the coatings and elemental compositions of the coatings were analyzed using X-ray diffraction (XRD), atomic force microscopy (AFM) and scanning electron microscopy (SEM) with energy dispersive X-ray spectroscopy (EDS). Total viable count (TVC) and epifluorescence microscopy analysis were studied to evaluate antimicrobial efficiency of ZrO2 and Ag–ZrO2 composite coatings using gram negative (gram −ve) Escherichia coli (E.coli) and gram positive (gram +ve) Staphylococcus aureus (S.aureus). On the basis of the present study, it could be speculated that ZrO2 coatings exhibited antibacterial activity against only E.coli, whereas Ag–ZrO2 composite coatings showed superior activity against E.coli and S.aureus strains.

Highlights

In recent years, the number of implant devices have increased for various implant surgeries takes leading effort across the world (Nathan et al 2012)
Nanostructured metal oxide thin films and metal complexes have emerged as class materials which are increasingly being studied for health-related applications
X-ray diffraction (XRD) examination reveals that monoclinic phase for ZrO2 and mixed phase for Ag– ZrO2 composite coatings were obtained

Summary

Introduction

The number of implant devices have increased for various implant surgeries takes leading effort across the world (Nathan et al 2012). The demands of implants have significantly increased for new patients and for patients who must receive revision surgeries. In order to improve bioactivity, biocompatibility and implant longevity, thin films which are having nano crystalline achieved considerable breakthrough in the field of biomedical sciences due to their exceptional physical and chemical properties (Holleck 1991). Nanostructured metal oxide thin films and metal complexes have emerged as class materials which are increasingly being studied for health-related applications. Ionic metal oxides are interesting in physical, chemical and antibacterial properties (Gu et al 2007; Jangra et al 2012)

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