Abstract
To investigate the phytochemicals present in the leaves of Datura innoxia and to assess its antioxidant and antibacterial properties in different organic solvents, leaf extracts were exposed to different standardized techniques. Folin–Ciocalteu method and Aluminium chloride method proved that the ethanolic extract has maximum phenolic content (72.35± 0.52 mg GAE/g) and flavonoid content (29.21± 1.25 mg EQ/g) respectively. The highest DPPH radical scavenging activity with IC50 value 91.398 µg/ml also was in the ethanolic extract as compared to methanol, hexane and chloroform extracts. Free radical scavenging and antioxidant property of extracts were observed in the sequence of ethanol>methanol>hexane>chloroform. There was a strong correlation between antioxidant activity with total phenolic (DPPH, R2 = 0.41; PPM, R2 = 0.25) and total flavonoid contents (DPPH, R2 = 0.39; PPM, R2=0.23). Ethanolic and methanolic extracts showed antibacterial potential against the tested pathogenic strains; Staphylococcus aureus and Escherichia coli with a zone of inhibition ranging between 16± 0.9 to 27.5±0.8 mm. This study has proved that ethanolic leaf extract of D. innoxia showed bacterial inhibition and antioxidant activities and this herb can be assessed as a potential therapeutic species.
Highlights
In the herbal medical plants, the Solanaceae family, consisting approximately of 2500 species, is placed at the top with its high ethnobotanical content which is extensively used by the modern scientific fraternity for the further exploration and invention of effective medicines (1–4)
Datura innoxia is a widespread annual plant from the Solanaceae family. It is a rarely explored plant and even recommended as a species to be eliminated in certain parts of the world such as South Africa, the Pacific region and the Isabella Islands (5-7)
D. innoxia is a per
Summary
In the herbal medical plants, the Solanaceae family, consisting approximately of 2500 species, is placed at the top with its high ethnobotanical content which is extensively used by the modern scientific fraternity for the further exploration and invention of effective medicines (1–4). Datura innoxia is a widespread annual plant from the Solanaceae family. It is a rarely explored plant and even recommended as a species to be eliminated in certain parts of the world such as South Africa, the Pacific region and the Isabella Islands (5-7). D. innoxia (Fig.1) is invasive in the Galapagos Islands, New Caledonia, China, Taiwan, Ethiopia, Namibia and South Africa. It is widely naturalized in the tropics and increasingly in temperate Europe and North America (12), but today so common in India (9-13).
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