Abstract
BackgroundOils in traditional medicine are important products and used routinely for therapeutic purposes. Rose oil (Rosa damascene Mill), a product of Persian medicine, is advised for the treatment of Infectious diseases related to the female genitourinary tract. In the present study, R. damascena petal oil, aqueous, and hydroalcoholic extracts were evaluated for their in vitro antibacterial and anti-Trichomonas vaginalis effects.MethodsAnti-trichomonas activity evaluation of extracts and oil were assayed by the Homocytometery method. Their antibacterial effects against Escherichia coli, methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa, and clinically isolated Group B Streptococcus were assayed by broth microdilution in 96-well plates.ResultsThe MIC of hydroalcoholic and aqueous extracts ranged from 25-50 and 25-100 mg/ml, respectively. Rose oil at all administered doses failed to show any antibacterial activity.ConclusionAll extracts and oil concentrations showed some degree of growth inhibition activity on T. vaginalis; however, hydroalcoholic extract was more efficient.
Highlights
Infectious diseases represent a serious health problem today and account for one-third of all deaths worldwide
The Minimal Inhibitory Concentration (MIC) of hydroalcoholic and aqueous extracts ranged from 25-50 and 25-100 mg/ml, respectively, and rose oil did not present any antibacterial activity against the strains tested
The results of this study show that all bacteria were resistant to rose oil
Summary
Infectious diseases represent a serious health problem today and account for one-third of all deaths worldwide. Traditional medicine is more acceptable than in the past. It is cheaper and more accessible than conventional treatment [6]. World Health Organization (WHO) supports traditional medicine because traditional literatures are source of treatment strategies for different people in the world [7]. Pharmaceutical manuscripts of Persian scholars contain various therapeutic dosage forms and treatment strategies. Over 100 dosage forms have been introduced in pharmaceutical literatures of Persian medicine but they need updates and quality controls [9, 10]. Oils in traditional medicine are important products and used routinely for therapeutic purposes. Rose oil (Rosa damascene Mill), a product of Persian medicine, is advised for the treatment of Infectious diseases related to the female genitourinary tract. R. damascena petal oil, aqueous, and hydroalcoholic extracts were evaluated for their in vitro antibacterial and anti-Trichomonas vaginalis effects
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