Antibacterial and antioxidant bio-based networks derived from eugenol using photo-activated thiol-ene reaction

Abstract

Bio-based networks derived from eugenol and linalool were prepared with an eco-friendly process by photoactivated thiol-ene reactions. Allyl derivative Eugenol, AE, prepared by a nucleophilic substitution was combined with linalool, L, a monoterpene presents in the lavender essential oil, well known to its antibacterial activity or with Eugenol, E, a sustainable antioxidant molecule major component of the essential oil of clove. The photoactivated thiol-ene reaction is a quick room temperature straightforward way to obtain renewable crosslinked networks. Two bacteria strains were used in vitro to evaluate the resistance to bacterial adhesion and the DPPH method was used to determine the antioxidant properties of the networks. As expected, the results showed a promising anti-adhesion activity against Staphylococcus aureus (S.aureus) and Escherichia coli (E. coli) due to the presence of eugenol moieties. Moreover, the phenol groups of eugenol provide an antioxidant activity characterized by a radical scavenging activity of 90%.