Abstract
Waltheria indica L., a member of Sterculiaceae family, is widely used traditionally to treat a variety of infections in humans. Roots of W. indica were collected from William Show farm, Blouberg Area-Limpopo Province, South Africa. Water, ethanol, methanol and acetone extracts were tested for antibacterial activity. Zones of inhibition ranged from 8.9 ± 0.79 to 20.2 ± 0.57 and were dose dependent. Methanol extract exhibited lowest of 0.52 mg/ml against Bacillus cereus. Ethanol extract exhibited lowest minimum bactericidal concentrations against B. cereus at 0.65 mg/ml. Methanol extract was also tested for antioxidant activity using 2, 2-diphenyl-1-picryhydrazyl (DPPH) radical scavenging assay and exhibited 75.45 ± 2.76 at a concentration of 0.75 mg/100 ml. DPPH inhibition was also found to be dose dependent. These biological activities observed in the selected extracts validate ethnomedicinal use of W. indica. Key words: Waltheria indica L, antibacterial, antioxidant, ethnomedicine
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