Abstract
Snails have been used both as a food and as a treatment for a variety of medicinal conditions. In this study, seven different snail proteins were evaluated for their antimicrobial activity. Fresh water and land snails of seven different live species were collected and identified. Crude proteins were extracted from seven different snails. The extracted proteins were estimated using Bradford’s method and snail proteins were displayed using a sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE) analysis. The seven different snail proteins were evaluated for their antimicrobial activity against various pathogenic bacterial and fungal cultures by agar well diffusion method and MIC (Minimum Inhibitory Concentration). One of the most active, crude proteins was from land snail Cryptozona bistrialis and its protein was capable of completely inhibiting the development of pathogenic bacterial and fungal cultures. This study shows that the land snail C. bistrialis proteins could be used as an antibiotic in biomedical research.
Highlights
Mollusks are an abundant and significant group in the trophic chain of the animal kingdom.Among mollusks, gastropods including snails and slugs, represent the most abundant class
One of the most active, crude proteins was from land snail Cryptozona bistrialis and its protein was capable of completely inhibiting the development of pathogenic bacterial and fungal cultures
This study shows that the land snail C. bistrialis proteins could be used as an antibiotic in biomedical research
Summary
Mollusks are an abundant and significant group in the trophic chain of the animal kingdom.Among mollusks, gastropods including snails and slugs, represent the most abundant class. Mollusks are an abundant and significant group in the trophic chain of the animal kingdom. Snails in particular are successful animals from an evolutionary point of view, having survived extreme environmental conditions for more than 600 million years, due to their capacity to adapt to different environments and to reach dry land [1]. This indicates that snails have some special adaptive proteins with which they are able to survive in their environment. Few extensive investigations have been made of the antimicrobial proteins of mollusks groups whole body homogenates of some marine mollusks have been reported to contain a variety of antimicrobial and antioxidant compounds
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